ceesdekker Can Be Fun For Anyone

ceesdekker Can Be Fun For Anyone

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Working with solitary-molecule optical and AFM imaging and force-spectroscopy techniques, we search for to unravel the mechanistic areas of the construction and dynamics of chromosomes. Our research pursuits incorporate:

Human Rad51 filaments on double- and single-stranded DNA: correlating common and irregular forms with recombination operate.

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Non-equilibrium folding of individual DNA molecules recaptured up to 1000 times in a good point out nanopore

2010, produced a whole new way (‘wedging transfer’) to govern nanostructures; to start with report of DNA translocation through graphene nanopores; and realized hybrid nanopores by directed insertion of α-hemolysin into sound-condition nanopores

Cornelis (Cees) Dekker (Haren, 7 april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en met 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.

All parameters were being the same for each panel On this movie, apart from the Original placement from the 6hb rod (proven in blue) about the nanopore. Simulations that terminated early resulting from translocation of your rod through the pore are marked by a grey background.

2011, initial in vitro measurements of transport across a single biomimetic nuclear pore elaborate; enhancement of multiplexed magnetic tweezers for kilo-molecule experiments; and fixed the system of homology recognition in DNA homologous recombination

The rotors harness Power from the nanoscale drinking water and ion movement that's created by a static chemical or electrochemical likely gradient inside the nanopore, which are founded by way of a salt gradient or used voltage, respectively. These synthetic nanoengines self-organize and run autonomously in physiological situations, suggesting ways to developing Electricity-transducing motors at nanoscale interfaces.

Bulk-surface coupling identifies the mechanistic link involving Min-protein styles in vivo As well as in vitro

[fourteen] In 2005 Dekker became involved with Netherlands-broad discussions about Smart Structure, a movement https://www.ceesdekker.net that he has considering the fact that Obviously distanced himself from. Dekker advocates that science and faith aren't in opposition but is often harmonized.

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2008, initially observation of protein-coated DNA translocation by nanopores; solved the origin with the electrophoretic pressure on DNA in nanopores; learned a big velocity raise of microtubules in electrical fields; identified an anomalous electro-hydrodynamic orientation of microtubules; and settled the origin of noise in carbon nanotubes in liquid

2013, managed shaping of Dwell bacterial cells into arbitrary shapes; and discovery of spontaneous fluctuations while in the handedness of histone tetrasomes